Reactive Attachment Disorder: Etiology, Symptoms, Affected Brain Areas and Treatment


 

radReactive Attachment Disorder (RAD) is characterized by considerably disturbed and inappropriate social interaction, across situations, that is manifested before the age of five (DSM-IV-R). Evidence for the disorder is usually seen in continuous failure to respond appropriately in social situations (being hypervigilant, inhibited, or ambivalent) and/or inability to develop and exhibit selective attachment to primary caregiver(s) (DSM-IV-R). The causes for the disturbed behavior in Reactive Attachment are associated with the developmental stages of Infancy and Early childhood, when pathogenic care can have profound and lasting effects. DSM-IV outlines three aspects of pathogenic care that explain the disturbance in normal development and behavior: persistent disregard for the child’s physical and emotional needs, as well as repeated changes of primary caregiver and/or surroundings. The connection between pathogenic care and disrupted behavior is compelling and reminds of the critical importance of nurture and effective parenting. Many psychologists have studied in depth child development during the first years of life and reveal that this is an extremely sensitive period for both physical and emotional development and maturation. It is a critical time for cultivating attachment, social skills, developing empathy and understanding basic values. 

 



How does Prozac function within the brain?


prozacProzak (fluoxetine) is among the Selective serotonin reuptake inhibitors (SSRIs), aka. second-generation antidepressants. As all SSRIs, Prozak blocks the reuptake transporter for serotonin, preventing it from being taken back to the axon terminal. Since this transporter is blocked, serotonin remains in the synaptic cleft for long periods, continuing to have its effect on the postsynaptic neuron. Although this effect takes place very quickly, depression symptoms take long periods to be alleviated. This phenomenon is not fully understood, but it’s interesting to note that Prozak increases the production of new neurons in the hippocampus - a limbic structure that is very vulnerable to stress-induced damage. Therefore, it is suspected that this renewal in the hippocampus is exactly the reason behind this antidepressant’s effect.



Warning: Mixing alcohol with anti-anxiety drugs - a deadly cocktail!


The danger is found in drugs’ effect on GABA receptors.

Drugs like alcohol, barbiturates, and benzodiazepines all seems to affect the same target – the major inhibitory neurotransmitter GABA. Neurons containing GABA KSM crack series still lifes 2receptors are very common in the nervous system and their function is to inhibit other neurons. One such receptor that is affected by GABA is the GABAa receptor that contains chloride channels. When the receptor is excited, an influx of Cl ions takes place, increasing the negative charge on the inside – hyperpolarization – making initiation, or propagation of an action potential much more difficult. However, this GABAa receptor has not only a binding site for GABA, but two other binding sites as well. One is the sedative-hypnotic site, the other is the anxiety site. That’s why it is possible that both sedative-hypnotic drugs (alcohol and barbiturates) and antianxiety drugs (benzodiazepines) can bind to the same receptor, amplifying their effects. Sedative-hypnotic drugs (alcohol or barbiturates) have precisely this effect -making it hard for action potential to take place and, therefore, sedating the body and affecting bodily functions. Antianxiety drugs (benzodiazepines) enhance binding effects of GABA and so alcohol, or barbiturates will have an even stronger sedative effect, possibly leading to coma, or even death.

The threat of mixing drugs and alcohol is not just a myth, it is a deadly cocktail that you don’t want to be experimenting with.




The Psychology of Deafness


 

signlanguage-handsUntil recently, the study of deafness has been viewed within a deficit model, with focus on the “almost invariably negative effects of a sensory impairment or deficit” (Gregory, Hartley, Constructing Deafness). In my opinion, this has been a largely distorted view of professionals who have had no experience within the deaf community and have only viewed deaf people as a group who is deviating from the norm. In a primarily male-dominated society, many events and medical conditions have not been properly studied and documented, simply because they have concerned and affected only women. Similar is the ignorance, misunderstanding and disregard for issues concerning deaf individuals in a primarily hearing world. In fact, the first attempts, at least in the field of Cognitive Psychology, to study deaf people have been done in effort to understand the functioning of the hearing. Throughout human history, there is a myriad of examples when minorities, or underprivileged people have been labeled as ‘different‘ and, therefore, not worth too much effort to be understood, or helped. Sadly, this appears to be a challenge even for scientists and researchers who, above all, should be dispassionate and objective observers and analyzers of phenomena and human behavior. Following the evolutionary perspective in Psychology, we can allude there is an inborn instinct in species to avoid something that is new, foreign and unfamiliar, as it might hurt us. Even if this is the case, humanity has walked a long way in this process of evolution and if we are to take pride in being highly civilized and humane, we are to try to understand the unfamiliar better before putting any sort of label. The population of the United States includes more than 1 million deaf people, most of whom chose to identify themselves as part of the Deaf culture. People within this culture really do share unique values and norms, and use American Sign Language as a primary way of communication (Stebnicki, Coeling, 1999). These are not people who want to be victimized, ignored or viewed as impaired and in many situation the only difference between a hearing and a deaf individual can be the different treatment that we have.



The Impact of the Enlightenment on the French and American Revolutions


age-of-reason-6191The eighteenth century, following the age of Reason, gave birth to a new philosophical, intellectual and cultural movement that transformed the mentality of people not only in the Old Continent, but in the New World alike. This era, known as the Age of Enlightenment, promoted human intellect, reasoning, liberty and virtue. The symbolism behind Enlightenment is found in the elaborate metaphor of light being cast upon the world to reveal the truth in science, social and political order, education and all other human affairs. Probably the best way to describe the spirit of this historically significant period is to view it from the eyes of its most pronounced thinkers. In his work, Immanuel Kant explains: “Enlightenment is man’s emergence from his self-imposed nonage. Nonage is the inability to use one’s own understanding without another’s guidance. This nonage is self-imposed if its cause lies not in lack of understanding but in indecision and lack of courage to use one’s own mind without another’s guidance. Dare to know! (Sapere aude) ‘Have the courage to use your own understanding’ is therefore the motto of the  Enlightenment.”



Achievement Motivation Inventory


motivationThe Achievement Motivation Inventory AMI (Schuler, Thornton, Frintrup & Mueller Hanson, 2004) is based on a new trait-oriented concept of Achievement Motivation that assumes it is build up of multiple interrelated components. Specifically, the Inventory employs 17 scales of measurement, 170 items total (each scale has ten items). The inventory is intended for use in work and employment context.

 

Accepting that achievement motivation is a personality construct, the authors of the AMI attempt to measure its different aspects that, expectedly, manifest themselves across situations. However, I am not convinced that achievement motivation is a rigid personality construct.



Fluid and Crystallized Intelligence


In studying Intelligence, researchers noticed that two correlated factors emerge: Crystallized and Fluid Intelligence. Charles Spearman, in particular, was the first to develop the concept of Fluid g (fg) and Crystallized g (cg). These two, in combination, appeared to explain one’s Intelligence. 



The Five Factor Theory of Personality


personality-typeThe Five Factor Theory was first introduced by McCrae and Costa (1984) and is based on the assumption that personality is relatively stable in adulthood. Generally, the traits that we show at the age of 30 would remain essentially unchanged into old age. (McCrae & Costa, Personality in Adulthood) Therefore, assessing personality based on the core traits what will not change through adult life seemed like a reliable method. There have been a lot of multi-cultural, cross-sectional and longitudinal studies throughout the past two decades. All of this research has confirmed the reliability and validity in the NEO Personality Inventory, or NEO-PI (Costa & McCrae, 1985, 1989a) and has postulated there are indeed universal personality traits that characterize people all over the world.



Antisocial Personality Disorder


All humans have traits that help describe our personality and predict behavior. Traits are consistent patterns of behavior that remain largely the same in changing situations. These are “well-ingrained ways in which individuals experience, interact with, and think about everything that goes on around them” (James Morrison, DSM-IV Made Easy). Personality disorders are manifested when a collection of traits has become rigid, works to the disadvantage of the individual, causes distress, or otherwise impairs functioning. There are 10 Personality disorders identified in the DSM-IV within 3 different cluster: Paranoid, Schizoid, Schizotypal, Antisocial, Borderline, Histrionic, Narcissistic, Avoidant, Dependent, Obsessive-Compulsive. The generic criteria for personality disorders consists of a lasting pattern or behavior and inner experience that deviates significantly from the norm of the culture. The pattern is most often manifested in affect/emotional experiences (Inappropriateness, intensity, lability and largely inappropriate range of emotions), cognition, impulse control and interpersonal functioning.

withoutconscience

Antisocial personality disorder is described in Cluster B of the DSM-IV (Diagnostic and Statistical Manual of the American Psychiatric Association, 4th edition). Along with the other personality disorders in this cluster, Antisocial personality is often characterized as dramatic, attention-seeking, and emotional; their moods being labile and often shallow. The irresponsible, often criminal behavior of these people begins in childhood or early adolescence with truancy, running away, cruelty, fighting, destructiveness, lying, and theft. In addition to criminal behavior, as adults they may default on debts, or otherwise show irresponsibility, act recklessly or impulsively; and show no remorse for their behavior (DSM-IV, p.474). People with Antisocial Personality, also called sociopaths or psychopaths, manifest a “pervasive pattern of disregard for and violation of the rights of others occurring since age 15” (DSM-IV). There is a failure to conform to social norms (with respect to lawful behaviors as indicated by repeatedly performing acts that are grounds for arrest). Their deceitfulness is indicated by repeatedly lying, using aliases or cunning others for personal profit or pleasure. Very often, these people have issues with impulse control/impulsivity (remember the Marshmallow study?) and planning ahead. Irritability and aggressiveness are other characteristic traits, as indicated by repeated physical fights or assaults. There is reckless disregard for safety of self and/or others. Consistent irresponsibility is observed as well as lack of remorse, being indifferent to being hurtful, or rationalizing their destructive behavior and mistreatment (Liane Leedom, “Just like his father”).

Research indicates there is a strong hereditary/genetic component to antisocial personality disorder. Therefore, children whose parent is a sociopath are considered “at risk” and a lot of efforts and extra care and attention are required.

Personality Disorders are probably the hardest to treat, since there is a problem within one’s own personality and core traits. No medication can alleviate the symptoms, only cure other issues that might spring from the personality disorder. Often the individual has to be willing to work with a therapist over a very long period of time, where change and improvement take place slowly. As one might imagine, an individual with Antisocial personality is, more often than not, unwilling to get in treatment or ‘seek help’ since they are incapable of finding the fault in their own ways.



The tools to study personality


 

personality1Axis II in DSM-IV versus the Five Factor Model

 

While it is true that both Axis II in DSM-IV and the Five Factor Model measure similar constructs, the main focus being one’s personality, they tend to investigate different aspects of personality. The use of DSM-IV and Axis II implicates the diagnosis of a particular personality disorder. Axis II has no interest in studying healthy individuals. Its main focus is identifying the real rigid traits that do not allow ‘normal’ functioning in life. DSM-IV, as a whole, provides the tools and the perspective required to diagnose psychological disorders, but it is not adapted to describing the wide spectrum of traits and qualities of a ‘healthy personality’.

 

The Five Factor Model, on the other hand, attempts to recognize and analyze all of the major traits that build up a person. This model is equally interested in studying healthy individuals as well as personality disorders (which is by no means the case with DSM-IV).

 

Axis II in DSM-IV provides a very detailed description of the disorders and informs abut their specific coding. The specific checkpoints and guidance make a diagnosis easier and, allegedly, more accurate.

 

The Five Factor model certainly has many advantages, as it is the one inventory that provides a full, very specific and realistic description of a personality, with all its nuances. Based on this description of traits, a lot can be effectively predicted about the behavior of the individual. The Five Factor Model is not limited to psychopathology, but investigates the whole continuum of a trait and so, sees subjects in every part of the belt curve. As the model is very precise in describing the big five traits (Openness, Conscientiousness, Extaversion, Agreeableness and Neuroticism), it can be of great help in therapeutic setting, revealing the areas that need ‘improvement’. After all, this is the most important part of any helping profession – how exactly do we help the individual? Not to underestimate, the Five Factor Model has an enormous body or research behind it, which has proven it is both a valid and reliable technique.